The role of the oxygen free radicals in contrast-induced nephropathy in the elderly: progress in research
10.3760/cma.j.issn.0254-9026.2021.03.027
- VernacularTitle:氧自由基在老年人造影剂肾病中作用的研究进展
- Author:
Ying LIU
;
Jihong YANG
;
Hong SHI
;
Jing LI
;
Hui WANG
;
Jiashun HUANG
;
Ji SHEN
;
Yang LIU
- From:
Chinese Journal of Geriatrics
2021;40(3):397-400
- CountryChina
- Language:Chinese
-
Abstract:
With the acceleration of the aging process in China, the incidence rates of coronary heart disease and cerebral infarction have significantly increased.And iodine contrast agent is often used in imaging diagnosis and percutaneous intervention therapy.The contrast medium is filtered from the glomerulus in its original form and is not absorbed by renal tubules.However, the accumulation of iodine contrast medium in the kidney can lead to acute kidney injury.Kidney is one of the most important excretory and endocrine organs in human body.The prevention and treatment of contrast-induced nephropathy(CIN)have been widely concerned.The incidence rate of contrast-induced renal damage is higher and the prognosis is poorer in the elderly than in the non-elderly due to the decline of organ function in the elderly.At present, the mechanism of action for oxygen free radicals in CIN of the elderly is still unclear.This article reviews the researches on the role of oxygen free radical in CIN of the elderly studied by domestic and foreign scholars in recent years.
