The role of estrogen and its membrane receptor G protein-coupled estrogen pathway in regulating glucose and lipid metabolism and imbalance of inflammatory response: The latest research progress
10.3760/cma.j.issn.0254-9026.2021.03.026
- VernacularTitle:雌激素及其膜性受体G蛋白偶联雌激素受体在糖脂代谢中的研究进展
- Author:
Xiaojing FENG
;
Chenyang WANG
;
Jing WU
- From:
Chinese Journal of Geriatrics
2021;40(3):393-396
- CountryChina
- Language:Chinese
-
Abstract:
G protein-coupled estrogen receptor(GPER), as a newly discovered estrogen membrane protein-coupled receptor, has attracted much attention in endocrine metabolism research in recent years.Abnormal glucose and lipid metabolism and imbalance of inflammatory response mediated by GPER is one of the pathogenesis mechanisms of various endocrine and metabolic diseases.GPER is expected to become a new drug target for the treatment of coronary atherosclerosis, obesity and diabetes.This article briefly reviews the progress of GPER-mediated estrogen signaling pathway in terms of glucose metabolism, lipid metabolism and inflammation.
