Research progress on radiotherapy combined with PD-1/PD-L1 inhibitors in the treatment of breast cancer
10.3760/cma.j.cn113030-20200329-00141
- VernacularTitle:乳腺癌放疗联合PD-1/PD-L1抑制剂研究进展
- Author:
Jie JIANG
;
Wei HUANG
- From:
Chinese Journal of Radiation Oncology
2021;30(4):424-428
- CountryChina
- Language:Chinese
-
Abstract:
Radiotherapy has been proven to enhance tumor-specific immune response and provide targets for immune drugs. Immune checkpoint inhibitors represented by PD-1/PD-L1 combined with radiotherapy can enhance anti-tumor activity and exert abscopal effect. In this article, research progress on the basic study and clinical trials and challenges of radiotherapy combined with PD-1/PD-L1 inhibitors in the treatment of breast cancer were reviewed.