Delayed Allergic Reaction to Secondary Administrated Epidural Hyaluronidase.
10.3344/kjp.2015.28.2.153
- Author:
A Reum PARK
1
;
Woong Mo KIM
;
Bong Ha HEO
Author Information
1. Department of Anesthesiology and Pain Medicine, Chonnam National University Medical School, Gwangju, Korea. bongha99@naver.com
- Publication Type:Brief Communication
- Keywords:
Allergy;
Epidural;
Hyaluronidase;
Hypersensitivity;
Pain;
Skin test
- MeSH:
Hyaluronoglucosaminidase*;
Hypersensitivity*;
Hypersensitivity, Delayed;
Skin Tests
- From:The Korean Journal of Pain
2015;28(2):153-155
- CountryRepublic of Korea
- Language:English
-
Abstract:
We are reporting a rare case of a delayed hypersensitivity reaction caused by hyaluronidase allergy following a lumbar transforaminal epidural block. Using an intradermal skin test, we have provided evidence that the systemic allergic reaction resulted from hypersensitivity to hyaluronidase. To our knowledge, this is a rare case of a delayed hypersensitivity reaction to epidural hyaluronidase, comprised of an initial exposure to hyaluronidase with no subsequent allergic response in prior block followed by a subsequent delayed reaction to hyaluronidase during a second epidural block.