Boron neutron capture therapy of cancers: principles and recent research progress
10.3760/cma.j.issn.0254-5098.2021.01.015
- VernacularTitle:肿瘤硼中子俘获治疗的理论基础与近期研究进展
- Author:
Di XU
;
Yucai ZHANG
;
Qiyi ZHOU
;
Li ZHAO
- From:
Chinese Journal of Radiological Medicine and Protection
2021;41(1):74-77
- CountryChina
- Language:Chinese
-
Abstract:
Boron neutron capture therapy (BNCT) is a new method for the precise treatment of cancers.By this method, cancer cells can be selectively killed by α particles and recoiling 7Li nuclei generated by the nuclear fission reaction occurring when the 10B isotope atoms in cancer cells capture thermal neutrons.The key to a successful BNCT is to deliver sufficient 10B into the cancer cells.The purpose of this review is to introduce the principles of BNCT and review recent progress in the development of neutron sources and boron delivery agents, as well as the result of BNCT clinical trials.
