Age-Related Differences of Spectral-Domain Optical Coherence Tomography Data in Koreans.
10.3341/jkos.2013.54.2.289
- Author:
Ji Young SUH
1
;
Hong Ryung SEO
;
Sae Heun RHO
Author Information
1. Department of Ophthalmology, Dong-A University College of Medicine, Busan, Korea. shrho@donga.ac.kr
- Publication Type:Original Article
- Keywords:
Optic disc parameter;
Retinal nerve fiber layer thickness;
Spectral-domain optical coherence tomography
- MeSH:
Eye;
Humans;
Optic Disk;
Tomography, Optical Coherence
- From:Journal of the Korean Ophthalmological Society
2013;54(2):289-295
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: We evaluated the thickness of RNFL and optic nerve head parameters with age in normal eyes using Spectral-Domain Optical Coherence Tomography (SD-OCT). METHODS: A total of 128 normal Korean volunteers in different age groups were recruited (age range, 20-70 years). RESULTS: A significant negative correlation in average RNFL thickness with increasing age was found. The inferior areas (130.31 +/- 3.33 micrometer) were significantly thicker than other areas (superior area 119.05 +/- 2.12 micrometer, nasal area 71.80 +/- 0.57 micrometer, temporal area 77.72 +/- 0.16 micrometer). The average C/D ratios (mean 0.38 +/- 0.14) and vertical C/D ratios (mean 0.35 +/- 0.11) both showed significant increases with age, and the vertical C/D ratio correlation coefficient was higher (average C/D ratio r = 0.249, vertical C/D ratio r = 0.537). However, rim area, disc area, and cup volume were not correlated with age. CONCLUSIONS: From these findings, we conclude that, in normal Koreans, the mean RNFL thickness decreases and the C/D ratio increases with age, with the increase in the vertical C/D ratio being greater.
