A Case of Propylthiouracil-Induced Lupus.
- Author:
Jaechun LEE
;
Bin YOO
;
Yun Jeong LIM
;
Seong Ho KIM
;
Mikyung LIM
;
You Sook CHO
;
Young Kee SHONG
;
Hee Bom MOON
- Publication Type:Case Report
- Keywords:
Graves' disease;
Drug-induced lupus;
Propylthiouracil
- MeSH:
Antibodies, Antinuclear;
Female;
Graves Disease;
Humans;
Propylthiouracil
- From:The Journal of the Korean Rheumatism Association
1999;6(1):75-78
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Propylthiouracil(PTU) is one of lupus-inducing drugs, though rarely reported. We report a case of PTU-induced lupus, with the review of of previous literatures. Lupus-like symptoms in a 28year-old female patient, who had been suffering from relapsed Graves' disease, were presented during PTU therapy. The results of antinuclear antibody and anti-histone antibody were positive. After symptomatic reatment and discontinuation of PTU, all of the symptoms and the abnormalities in laboratory tests disappeared, which suggested drug-induced lupus.
