Research progress on the relationship between metabolism related fatty liver disease and chronic hepatitis C
10.3760/cma.j.cn101721-20201016-00020
- VernacularTitle:代谢相关脂肪性肝病和慢性丙型病毒性肝炎的相关性研究进展
- Author:
Shuang ZHENG
;
Yiling LI
- From:
Clinical Medicine of China
2021;37(2):180-184
- CountryChina
- Language:Chinese
-
Abstract:
Metabolic related fatty liver disease(MAFLD) is a kind of fatty liver disease caused by metabolic dysfunction closely related to insulin resistance and genetic susceptibility, also known as nonalcoholic fatty liver disease (NAFLD). Chronic hepatitis C (CHC) is a worldwide curable viral hepatitis caused by hepatitis C virus (HCV) infection.If MAFLD is combined with CHC, CHC can lead to insulin resistance, increase the oxidative stress of hepatocytes, accelerate the steatosis of hepatocytes, and affect the therapeutic effect of MAFLD.
