Research progress of liver X receptors in lipid metabolism
10.3760/cma.j.cn101721-20200309-00060
- VernacularTitle:肝X受体在脂质代谢中的研究进展
- Author:
Yufa FANG
;
Jin FENG
;
Yankai ZHOU
;
Yaling XU
;
Fangyan HE
- From:
Clinical Medicine of China
2021;37(1):88-92
- CountryChina
- Language:Chinese
-
Abstract:
The imbalance of lipid metabolism is an important factor causing a series of metabolic diseases such as non-alcoholic fatty liver disease (NAFLD) and hyperlipidemia.Liver X receptors is a member of the nuclear receptor superfamily, which maintains cholesterol homeostasis by regulating cholesterol absorption, transport, reverse cholesterol transport, biosynthesis and other functions.It plays an important role in maintaining lipid homeostasis by regulating de novo fat synthesis to maintain the balance of fatty acids in the body.
