Correlation between serum high sensitivity C-reactive protein and carotid intima-media thickness

VernacularTitle:血清超敏C反应蛋白水平与颈动脉内膜中层厚度的相关性分析
Author: Ying ZHANG ; Xin DU ; Jie LI ; Lin MA ; Shuhua ZHANG ; Shouling WU ; Chunpeng JI ; Jihong SHI ; Rui GUO
From: Clinical Medicine of China 2021;37(1):26-30
CountryChina
Language:Chinese
Abstract: Objective:To investigate the correlation between serum high sensitivity C-reactive protein and carotid intima-media thickness.Methods:A total of 5 136 health examination subjects, aged ≥40 years old, who met the inclusion criteria and had complete data, were selected as the research objects.A unified questionnaire survey, blood biochemistry and carotid artery color doppler ultrasound examination were performed.According to the diagnostic criteria of hs-CRP published by American Heart Association (AHA), the subjects were divided into three groups: 0.05 mg/L0.84 mm group.The results showed that when the concentration of hs-CRP was high, CIMT increased with the increase of hs-CRP( OR(95% CI) 1.24 (1.01~1.52), P<0.05). Conclusion:There was a positive correlation between hs-CRP and CIMT.Patients with higher levels of hs-CRP are more likely to develop CIMT thickening and increase the risk of arteriosclerotic disease.