The research progress on risk factors of bleeding transformation after arteprase intravenous thrombolysis in elderly patients with acute ischemic stroke

VernacularTitle:高龄急性缺血性脑卒中阿替普酶静脉溶栓后出血转化的危险因素研究进展
Author: Yang LYU ; Sishan GAO ; Jijun TENG
From: Journal of Chinese Physician 2021;23(4):637-640,f3
CountryChina
Language:Chinese
Abstract: Acute ischemic stroke has become one of the important causes of death and disability in human beings, especially in elderly patients. Intravenous thrombolysis with alteplase is an important treatment. However, there are many underlying diseases and poor overall conditions in elderly patients, which increase the risk of intracranial hemorrhage. Intracranial hemorrhage transformation makes the patient′s condition worse, which is the most serious complication of alteplase intravenous thrombolysis, and also one of the important reasons for the low treatment rate of alteplase intravenous thrombolysis in elderly patients. Therefore, we need to pay close attention to the occurrence mechanism and risk factors of intracranial hemorrhage transformation after alteplase intravenous thrombolysis in elderly patients, so as to reduce the risk of intracranial hemorrhage transformation, improve the prognosis and reduce the risk of morbidity and mortality.