The relationship between red blood cell distribution width and metabolic syndrome in patients with impaired glucose tolerance

Zhen Zhang; Weidong Zhou; Shenglan WU; Jinying Yang; Yuhui Peng; Jiannan Xiang; Can Chen; Jing TU

Return

The relationship between red blood cell distribution width and metabolic syndrome in patients with impaired glucose tolerance

VernacularTitle:糖耐量异常患者的红细胞体积分布宽度与代谢综合征的相关性
Author: Zhen ZHANG ; Weidong ZHOU ; Shenglan WU ; Jinying YANG ; Yuhui PENG ; Jiannan XIANG ; Can CHEN ; Jing TU
From: Journal of Chinese Physician 2021;23(4):525-528
CountryChina
Language:Chinese
Abstract: Objective:To evaluate the relationship between red blood cell distribution width (RDW) and metabolic syndrome (MS) in patients with impaired glucose tolerance (IGT).Methods:A total of 415 patients with abnormal glucose tolerance were screened by oral glucose tolerance test in Changsha Traditional Chinese Medicine Hospital (Changsha Eighth Hospital) from October 2015 to September 2019. General data were collected and blood routine and biochemical indexes were detected. There were 193 cases in the observation group and 222 cases in the control group. The RDW and other clinical indicators were compared between the two groups, the correlation between RDW and other indicators was analyzed, and the risk factors of metabolic syndrome were analyzed.Results:⑴ The RDW, systolic blood pressure (SBP), diastolic blood pressure (DBP), height (Ht), weight (Wt), waist circumferenc (Wc), triglyceride (TG), cholesterol (CHOL), low density lipoprotein (LDL), creatinine (Cr), uric acid (UA), alanine aminotransferase (ALT), high sensitive C-reactive protein (hs-CRP), body mass index (BMI) of the observation group were significantly higher than those of the control group, while the high density lipoprotein (HDL) was significantly lower than that of the control group, with statistically significant difference ( P<0.05); ⑵ correlation analysis showed that RDW was positively correlated with SBP, DBP, Ht, Wt, Wc, TG, CHOL, Cr, UA, ALT, hs-CRP, BMI, and negatively correlated with HDL ( P<0.05); ⑶ binary logistic regression analysis showed that RDW, Wt, Wc, CHOL, HDL, LDL and hs-CRP were independent risk factors for MS in patients with impaired glucose tolerance. Conclusions:The increase of RDW is a predictor of metabolic syndrome in people with abnormal glucose tolerance, which may provide some reference value for the prevention and treatment of metabolic syndrome.