Progress in pathological mechanism of hypertrophic cardiomyopathy
10.3760/cma.j.cn431274-20201112-01531
- VernacularTitle:肥厚型心肌病病理机制的研究进展
- Author:
Jingchao LEI
;
Ying WEN
;
Xiaoyan LI
;
Xuejun JIANG
- From:
Journal of Chinese Physician
2021;23(3):474-477
- CountryChina
- Language:Chinese
-
Abstract:
Hypertrophic cardiomyopathy (HCM) is a cardiomyopathy characterized by non-secondary asymmetric hypertrophy of the ventricle, most of which manifests as autosomal dominant inheritance, and it is the main cause of sudden death in young athletes. In recent years, HCM has attracted much attention in epidemiology and molecular mechanism of pathogenicity. This article reviews the epidemiology, pathogenesis and clinical manifestations of HCM.