A Case of a Kidney Transplant Recipient with Pulmonary Cytomegalovirus and Nocardia Coinfection with Cytomegalovirus Nephropathy.
- Author:
Inwhee PARK
1
;
Hyunee YIM
;
Lim Seung KWAN
;
Sukyong YU
;
Jinhee CHO
;
Heungsoo KIM
;
Gyu Tae SHIN
Author Information
1. Department of Nephrology, Ajou University School of Medicine, Suwon, Korea. gtshin@ajou.ac.kr
- Publication Type:Case Report
- Keywords:
Cytomegalovirus;
Nocardia;
Kidney transplantation
- MeSH:
Biopsy;
Bronchiolitis Obliterans;
China;
Coinfection;
Creatinine;
Cytomegalovirus;
Diabetes Mellitus;
Fever;
Humans;
Kidney;
Kidney Failure, Chronic;
Kidney Transplantation;
Korea;
Lung;
Nocardia;
Opportunistic Infections;
Peritoneal Dialysis;
Pneumonia;
Thorax;
Transplants;
Tuberculosis, Pulmonary
- From:Korean Journal of Nephrology
2009;28(2):161-165
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
This is the first reported case of a kidney transplant patient in Korea who developed cytomegalovirus and Nocardia pulmonary coinfection simultaneously with cytomegalovirus nephropathy. The patient had a history of end stage renal disease on peritoneal dialysis, diabetes mellitus and pulmonary tuberculosis. He underwent unrelated living kidney transplantation in China. About 5 months after transplantation, he developed high fever and rising serum creatinine for which he was admitted to hospital. Chest CT revealed consolidation in the left upper lung field and lung biopsy showed CMV infected bronchiolitis obliterans with organizing pneumonia. Culture of lung biopsy tissue grew Nocardia farcinica. In addition, he was found to have CMV infection in kidney tissue with positive CMV antigen assay of blood. This case emphasizes that CMV infection, through its effect on systemic immunity, may increase the risk of other opportunistic infection.
