A Case of Malignant Melanoma with Multiple Myeloma.
10.5021/ad.1993.5.2.133
- Author:
Heung Ryeol CHOI
;
Yoon Whoa CHO
;
Sang Jang LEE
;
Byung In RO
;
Seong Hong KIM
- Publication Type:Case Report
- Keywords:
Malignant melanoma;
Multiple myeloma
- MeSH:
Biopsy;
Bone Marrow;
Drug Therapy;
Hemorrhage;
Humans;
Korea;
Male;
Melanocytes;
Melanoma*;
Middle Aged;
Multiple Myeloma*;
Paraproteinemias;
Plasma Cells;
Proteinuria;
Skin;
Transplants;
Vincristine
- From:Annals of Dermatology
1993;5(2):133-136
- CountryRepublic of Korea
- Language:English
-
Abstract:
Malignant melanoma is an uncommon tumor in Korea. To the best of our knowledge, we could not find malignant melanoma with multiple myeloma in Korean literature. A 57-year-old male patient had a 4×5 cm sized, irregular bordered, dark brownish plaque on the left sole, which has extended gradually since about 1 year ago and showed an occasional bleeding tendency. Laboratory examinations revealed a low hemoglobin level, rouleaux formation on peripheral blood, monoclonal gammopathy of IgG-kappa type and Bence-Jones proteinuria. Bone marrow aspiration findings showed markedly increased immature plasma cells suggesting multiple myeloma. Histopathologic findings of the skin biopsy from the left sole revealed proliferation of atypical melanocytes. We performed a surgical excision with a skin graft for malignant melanoma and chemotherapy (melphalan, vincristine and prednisolone) for multiple myeloma.
