Research progress of hepatic arterial infusion chemotherapy in the conversion therapy of hepatocellular carcinoma
10.3760/cma.j.cn115610-20201230-00813
- VernacularTitle:肝动脉灌注化疗在肝癌转化治疗中的研究进展
- Author:
Minshan CHEN
;
Zili HU
- From:
Chinese Journal of Digestive Surgery
2021;20(2):171-177
- CountryChina
- Language:Chinese
-
Abstract:
Primary liver cancer is the fourth most common malignancy and the second most common cause of cancer death in China, posing a serious threat to the health of Chinese people. Hepatocellular carcinoma (HCC) represents more than 90% of primary liver cancers, among them 66% of patients are with intermediate-advanced HCC. Therefore, prevention strategies and conversion therapies to patients with intermediate-advanced HCC are particularly important. Hepatic arterial infusion chemotherapy (HAIC) is one of the important treatment methods to treat intermediate-advanced HCC. The tumor objective response rates and surgery conversion rates of HAIC-based conversion therapies are promising. The authors review the history of HAIC and the HAIC-based conversion therapies in this article.