Prognostic neurodevelopmental outcome accuracy of amplitude-integrated electroencephalogram in premature infant: a Meta-analysis
10.3760/cma.j.issn.1673-4912.2021.05.015
- VernacularTitle:振幅整合脑电图预测早产儿远期不良神经发育预后的Meta分析
- Author:
Jie WANG
;
Yandong FENG
;
Zhongbin TAO
;
Baoling WANG
;
Li ZHOU
;
Ruijuan WANG
;
Yun ZHAO
- From:
Chinese Pediatric Emergency Medicine
2021;28(5):410-414
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the prognostic value of amplitude-integrated electroencephalogram(aEEG) on predicting long-term neurodevelopmental outcome of preterm infants.Methods:Literatures were searched in PubMed, the Cochrane library, Web of science, Wanfang database, CNKI and CBM database from inception to August, 2020.The studies which investigated the prognostic value of aEEG on neurodevelopmental outcome of preterm infants were included.Articles screening, data extraction and quality assessment were accomplished by two investigators independently, and statistical analyses were performed by Meta-disc1.4.Results:Six studies were included with 557 cases.The Meta-analysis revealed that the pooled sensitivity was 0.81 (95% CI 0.75-0.87), specificity was 0.68 (95% CI 0.63-0.73), positive likelihood ratio was 2.32(95% CI 1.52-3.52), negative likelihood ratio was 0.27(95% CI 0.19-0.37)and the area under the curve of summary receiver operating characteristic curve was 0.79(95% CI 0.75-0.82). Burst-suppression, continuous low voltage and flat trace were regard as a index of poor neurodevelopmental prognosis. Conclusion:aEEG is a valuable tool for predicting the outcome of long-term neurodevelopment in preterm infants.
