Clinical application of regional citrate anticoagulation for continuous renal replacement therapy in children with liver failure
10.3760/cma.j.issn.1673-4912.2021.04.020
- VernacularTitle:局部枸橼酸抗凝在肝衰竭儿童连续肾脏替代治疗中的临床应用
- Author:
Fang HU
;
Ke BAI
;
Chengjun LIU
- From:
Chinese Pediatric Emergency Medicine
2021;28(4):333-336
- CountryChina
- Language:Chinese
-
Abstract:
Continuous renal replacement therapy has become an important organ support method for children with liver failure.Anticoagulation is a key step in determining the success of this treatment.Traditional systemic heparin anticoagulation has a high risk of inducing thrombocytopenia and bleeding.Protamine antagonistic heparin local anticoagulation performance is unsatisfactory.Anticoagulation without heparin is difficult to develop smoothly in children, especially low-weight infants.In recent years, regional citrate anticoagulation has gradually received attention as a new type of anticoagulation.This article reviewed the clinical application of this anticoagulation technology.
