Clinical manifestations and pathogenesis of mycoplasma pneumoniae-associated extrapulmonary complications in children
10.3760/cma.j.issn.1673-4912.2021.01.002
- VernacularTitle:儿童肺炎支原体相关肺外并发症临床表现及发病机制
- Author:
Yang HU
;
Chunfeng LIU
- From:
Chinese Pediatric Emergency Medicine
2021;28(1):7-11
- CountryChina
- Language:Chinese
-
Abstract:
Mycoplasma pneumonia is the smallest free-living and self-replicating prokaryotic microbe being devoid of cell wall, which can not only lead to respiratory system diseases in human, but also play an important role in a wide variety of extrapulmonary diseases, involving cardiovascular, neurological, digestive, skin, hematological systems, and so on.However, the pathomechanisms of mycoplasma pneumonia-related extra-pulmonary diseases(MpEPDs) remain largely unknown.Yet there are three main possible pathomechanisms of mycoplasma pneumonia causing MpEPDs: direct type, immune type and vascular occlusion.They are connected with each other and cooperate on promoting MpEPDs, especially in children and the young.Comprehensive therapeutic strategies cover microbiology, immunology and anticoagulants, while supportive treatments are necessary.Most patients recover from MpEPDs have a favorable prognosis.
