Metabolic bone disease of prematurity: diagnosis and management
10.3760/cma.j.issn.1673-4912.2021.01.011
- VernacularTitle:早产儿代谢性骨病诊治的研究进展
- Author:
Chong LI
;
Jianhua FU
- From:
Chinese Pediatric Emergency Medicine
2021;28(1):50-54
- CountryChina
- Language:Chinese
-
Abstract:
Metabolic bone disease(MBD) in preterm infant is a disorder of calcium and phosphorus metabolism that leads to a decrease in bone mineral content, resulting in clinical, biochemical, and imaging changes.It occurs mostly in very low birth weight and extremely low birth weight newborns.The clinical symptoms usually occur from 6 to 12 weeks after birth, mainly manifested as dyspnea accompanied by mechanical ventilation for a long time, rickety-like changes, and even fracture in severe cases.At present, diagnosis of MBD is characterized by biochemical markers, radiology and ultrasound.As the clinical manifestations of MBD in prematurity occur late, early screening and prevention for high-risk groups play an important role to reduce the risk of MBD.
