Tooth-derived bone graft material.
10.5125/jkaoms.2013.39.3.103
- Author:
Young Kyun KIM
1
;
Junho LEE
;
In Woong UM
;
Kyung Wook KIM
;
Masaru MURATA
;
Toshiyuki AKAZAWA
;
Masaharu MITSUGI
Author Information
1. Department of Oral and Maxillofacial Surgery, Section of Dentistry, Seoul National University Bundang Hospital, Seongnam, Korea.
- Publication Type:Review
- Keywords:
Tooth;
Dentin;
Demineralized dentin matrix;
Bone substitutes;
Tissue engineering
- MeSH:
Bone Substitutes;
Dentin;
Intercellular Signaling Peptides and Proteins;
Proteins;
Stem Cells;
Tissue Engineering;
Tooth;
Transplants
- From:Journal of the Korean Association of Oral and Maxillofacial Surgeons
2013;39(3):103-111
- CountryRepublic of Korea
- Language:English
-
Abstract:
With successful extraction of growth factors and bone morphogenic proteins (BMPs) from mammalian teeth, many researchers have supported development of a bone substitute using tooth-derived substances. Some studies have also expanded the potential use of teeth as a carrier for growth factors and stem cells. A broad overview of the published findings with regard to tooth-derived regenerative tissue engineering technique is outlined. Considering more than 100 published papers, our team has developed the protocols and techniques for processing of bone graft material using extracted teeth. Based on current studies and studies that will be needed in the future, we can anticipate development of scaffolds, homogenous and xenogenous tooth bone grafts, and dental restorative materials using extracted teeth.
