Nursing care of patients with neuromyelitis optica spectrum diseases treated with immunoadsorption therapy
10.3760/cma.j.cn211501-20200319-01276
- VernacularTitle:视神经脊髓炎谱系疾病患者免疫吸附治疗的护理
- Author:
Lili LI
;
Hengfang RUAN
;
Liping SHEN
;
Jun ZUO
;
Wei QIU
- From:
Chinese Journal of Practical Nursing
2021;37(4):286-290
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the application and nursing of protein A immunosorbent in patients with neuromyelitis optica spectrum diseases.Methods:Ten patients with neuromyelitis optica spectrum diseases were treated with protein A immunoadsorption therapy. Psychological nursing was emphasized. Comprehensive evaluation was conducted before adsorption to determine the prescription of adsorption therapy. During adsorption therapy, hypotension, membrane rupture and hemolysis of plasma separator, shivering and other adverse reactions were accurately prevented and treated. After treatment, attention should be paid to the prevention of nosocomial infection, regeneration and preservation of adsorption column.Results:After immunoadsorption therapy, the serum IgG level, antibody and EDSS score of 10 patients decreased to varying degrees. The serum IgG decreased from (6.04±2.77)g/L to (2.23±1.74)g/L. No serious complications occurred, no failure of immunosorbent operation, and the patients′ condition was better than before.Conclusions:Protein A immunosorbent therapy for neuromyelitis optica spectrum diseases is safe and effective. Standardized evaluation, operation and nursing are the key to achieve good results.