Significance of thrombocytopenia in assessment of the severity and prognosis of sepsis
10.3760/cma.j.cn101070-20191008-00946
- VernacularTitle:血小板减少在脓毒症严重程度和预后判断中的意义
- Author:
Juan ZHU
;
Yang WANG
;
Qiyi ZENG
- From:
Chinese Journal of Applied Clinical Pediatrics
2021;36(5):391-393
- CountryChina
- Language:Chinese
-
Abstract:
Sepsis is a life-threatening organ dysfunction caused by dysregulation of the host response due to infection, and it can further develop into septic shock.Currently, sepsis is still a leading cause of death in children all over the world.Therefore, early assessment of the severity and prognosis of sepsis is of great significance.However, there are no indexes with high sensitivity and specificity for evaluating the severity and prognosis of sepsis at present.In recent years, a large number of studies have revealed the essential role of platelets in sepsis.It has been reported that the platelet count is an independent factor affecting the severity and prognosis of sepsis patients.Up to now, the specific mechanism of sepsis-induced thrombocytopenia has not been fully clarified.In this review, the value of thrombocytopenia in predicting the severity and prognosis of sepsis patients was elaborated.
