Application of gonadotropin-releasing hormone analogues in children with central precocious puberty
10.3760/cma.j.cn101070-20200603-00931
- VernacularTitle:促性腺激素释放激素类似物在儿童中枢性性早熟中的应用
- Author:
Guanping DONG
;
Junfen FU
- From:
Chinese Journal of Applied Clinical Pediatrics
2021;36(4):241-243
- CountryChina
- Language:Chinese
-
Abstract:
Gonadotropin-releasing hormone (GnRH) dependent precocious puberty/central precocious puberty (GDPP/CPP) is one of the common diseases of the pediatric endocrine system.CPP is mainly treated with gonadotropin-releasing hormone analogues (GnRHa) internationally.They slow the progression of bone age and improve adult height in children with CPP by inhibiting the activity of the hypothalamic-pituitary-gonadal axis and the secretion of sex hormones.In clinical practice, the populations who benefit from GnRHa treatment and the best GnRHa treatment plan still need to be investigated, and the long-term efficacy and safety evidence of GnRHa should be further improved.
