Study progress of microRNAs in aplastic anemia
10.3760/cma.j.cn101070-20190805-00713
- VernacularTitle:微小RNA在再生障碍性贫血中的研究进展
- Author:
Zhenghong LIU
;
Zhiliang XU
- From:
Chinese Journal of Applied Clinical Pediatrics
2021;36(3):228-230
- CountryChina
- Language:Chinese
-
Abstract:
Aplastic anemia (AA) refers to a life-threatening bone marrow failure disorder.With respect to the precise pathophysiology of AA at present, it is still unclear.MicroRNA (miRNA), about 22 nucleotides in length, is a kind of small RNAs and it can regulate gene expression post-transcriptionally.According to domestic and foreign reports recently, there are abnormal expressions of several miRNAs in AA patients, suggesting that miRNAs may be involved in the development and progression of AA.This article reviews the study progress of miRNAs in AA.
