The characteristics and treatment of rare embryonal tumors of central nervous system in children
10.3760/cma.j.cn101070-20201123-01792
- VernacularTitle:儿童少见中枢神经系统胚胎性肿瘤发病特点及治疗
- Author:
Yan SU
;
Xiaoli MA
- From:
Chinese Journal of Applied Clinical Pediatrics
2021;36(3):168-171
- CountryChina
- Language:Chinese
-
Abstract:
Embryonal tumors of central nervous system (CNS) are highly invasive malignant tumors that mainly affect infants.Even if the current active treatment strategies are given, the prognosis is still very poor.The 2016 World Health Organization(WHO) classification integrates the genetic information of diseases with histopathology, so as to make the classification and diagnosis of these tumors more accurate.In the new classification, embryonal tumors of CNS include the most common medulloblastoma, and the rare embryonal tumor with multilayered rosettes, C19MC-altered, embryonal tumor with multilayered rosettes, not otherwise specified (NOS), medulloepithelioma, CNS neuroblastoma, CNS ganglioneuroblastoma, CNS embryonal tumor, NOS, atypical teratoid rhabdoid tumor, and CNS embryonal tumor with rhabdoid features.Further study and exploration on the biological nature of these rare brain tumors will provide scientific basis for new treatment methods.
