Pediatric primary central nervous system lymphoma
10.3760/cma.j.cn101070-20201102-01705
- VernacularTitle:儿童原发性中枢神经系统淋巴瘤
- Author:
Yijin GAO
- From:
Chinese Journal of Applied Clinical Pediatrics
2021;36(3):161-164
- CountryChina
- Language:Chinese
-
Abstract:
Primary central nervous system lymphoma (PCNSL) is a form of extranodal non-Hodgkin lymphoma (NHL) and it is typically confined to brain, spinal cord, cranial nerves, eyes, and meninges without evidence of system spread.It is a rare subtype of NHL in childhood and adolescence, with an increased risk among patients with immunodeficiency.In the absence of prospective pediatric clinical trials, data from recent pediatric series and adult prospective trials was summarized, so as to help audience better understand the role of surgery, whole brain radiation therapy, and chemotherapy in the treatment as well.