Mechanism of inhibitory effect of interferon and its related signal pathway on the invasion of glioma

VernacularTitle:干扰素及其相关信号通路抑制脑胶质瘤侵袭的机制
Author: Yanqi SUN ; Yeqing REN ; Geng GUO
From: Journal of International Oncology 2021;48(3):172-175
CountryChina
Language:Chinese
Abstract: Glioma is a tumor with a high incidence of intracranial tumor. Because of its high degree of malignancy, strong invasiveness and high mortality, the current conventional treatment cannot achieve the desired therapeutic effect, which greatly affects the quality of life of patients. As a protein with the functions of anti-proliferation, anti-angiogenesis and anti-invasion, interferon is widely used in the treatment of all kinds of tumors in clinic. Many studies have shown that interferon plays an important role in the occurrence and development of gliomas. To explore the mechanism of interferon and its related signal pathway in the process of glioma invasion, and to study the new treatment of glioma is very necessary in clinical treatment.