Enrichment methods and clinical application of circulating tumor cells
10.3760/cma.j.cn371439-20200629-00033
- VernacularTitle:循环肿瘤细胞的富集方法与临床应用
- Author:
Dawei NING
;
Yang OU
;
Kai CUI
;
Sheng LI
;
Dehai GAO
- From:
Journal of International Oncology
2021;48(3):167-171
- CountryChina
- Language:Chinese
-
Abstract:
As an emerging tumor marker, the rarity and heterogeneity of circulating tumor cells (CTCs) increase the difficulty of detection. In recent years, CTCs enrichment technology based on biophysical, biochemical and microfluidic properties has been continuously developed, which has promoted the research and application of CTCs in malignant tumors diagnosis, clinical treatment and prognosis evaluation. Although there are still some deficiencies in the detection of CTCs, with the interdisciplinary integration, CTCs will play increasingly important roles in the diagnosis and treatment of malignant tumors.