Application of stem cells - 3D scaffold complex in wound dressing

VernacularTitle:干细胞-3D支架复合物在伤口敷料中的应用
Author: Fengqin LIU ; Song WANG
From: International Journal of Surgery 2021;48(5):339-345
CountryChina
Language:Chinese
Abstract: The clinical treatment of large-area trauma or intractable wound is very difficult. Finding a suitable wound dressing is very important for wound healing. Stem cells can secrete and express a variety of cytokines necessary for wound healing, and can grow and proliferate for a long time in three-dimensional (3D) scaffold materials to maintain their proper structure and function. A large number of studies have shown that transplanting stem cells-3D scaffold complex into the skin wound in the form of a moist dressing can significantly improve the efficiency of stem cells transplantation, shorten the wound healing time, and reduce scar formation. Stem cells-scaffold complex are likely to be a good wound dressing. This article mainly summarizes the selection of wound dressing and the research status of stem cells-3D scaffold complex as a wound dressing, aiming to provide a theoretical basis for the clinical application of stem cells-3D scaffold complex.