Radiation ulcers and other chronic wounds.
10.5124/jkma.2015.58.9.801
- Author:
Na Hyun HWANG
1
;
Jae Ho CHUNG
;
Deok Woo KIM
Author Information
1. Department of Plastic and Reconstructive Surgery, Korea University Medical Center, Korea University College of Medicine, Ansan, Korea. deokwookim@gmail.com
- Publication Type:Review
- Keywords:
Radiotherapy;
Radiation;
Radiation damage;
Wounds and injuries
- MeSH:
Drug Therapy;
Fibrosis;
Lymphedema;
Radiation, Ionizing;
Radiotherapy;
Skin;
Ulcer*;
Wound Healing;
Wounds and Injuries*
- From:Journal of the Korean Medical Association
2015;58(9):801-808
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Radiation ulcers are wounds caused by acute or chronic effects of ionizing radiation. The injury may involve the skin, underlying soft tissue, and even deeper into bones. Radiation is used alone or in combination with surgery and chemotherapy. Although it is useful to affect tumor death, it also exerts a deleterious effect on surrounding normal tissues. These effects are either acute or can manifest months or years after the treatment. The chronic wounds are a result of impaired wound healing. This impairment leads to fibrosis, nonhealing ulcers, lymphedema and radionecrosis amongst others.
