Research progression in the application of radiotherapy in the comprehensive treatment of diffuse gastric cancer
10.3760/cma.j.issn115396-20201019-00320
- VernacularTitle:放疗在弥漫型胃癌综合治疗中的应用研究进展
- Author:
Gang CHEN
;
Minmin ZHANG
;
Junmin ZHU
;
Yumin LI
- From:
International Journal of Surgery
2021;48(2):123-128
- CountryChina
- Language:Chinese
-
Abstract:
The incidence of diffuse gastric cancer is increasing year by year, comprehensive therapy is the main treatment. The main reason of surgical treatment failure is local recurrence, and the long-term curative effect is generally poor. Radiotherapy is an important part of comprehensive treatment for diffuse gastric cancer, which can reduce tumor stage before surgery and prevent recurrence and metastasis after surgery. Effective neoadjuvant radiotherapy is one of the approaches to improve surgical resection rate in patients with diffuse gastric cancer. In this paper, the clinical application of radiotherapy for diffuse gastric cancer will be reviewed, including the selection of reasonable radiotherapy system, precise location, dose setting, application of sensitization technology and mechanism of sensitization, in addition, the prevention and treatment of neoadjuvant radiotherapy and radiotherapy complications will be introduced.