Research progression in the mechanism of upper gastrointestinal hemorrhage in decompensated liver cirrhosis
10.3760/cma.j.cn115396-20201022-00325
- VernacularTitle:肝硬化失代偿期上消化道出血的机制研究进展
- Author:
Minmin ZHANG
;
Gang CHEN
;
Junmin ZHU
;
Bin ZHAO
;
Lijuan LIANG
- From:
International Journal of Surgery
2021;48(1):50-54
- CountryChina
- Language:Chinese
-
Abstract:
Liver cirrhosis in China can be caused by many causes of which the most important one is chronic viral hepatitis. Hemorrhage and ascites were the main manifestations of decompensated liver cirrhosis, and the main cause of hemorrhage is viral hepatitis. The pathological basis of hemorrhage is portal hypertension and its secondary pathophysiological changes. Additionally, the deficiency of coagulation factors and the imbalance of coagulation and fibrinolysis both of which caused by the hypofunction of liver are also important reasons. This article reviews the mechanism of hemorrhage in decompensated liver cirrhosis in order to provide help for further research.
