Long non-coding RNA H19: a therapeutic target for ischemic stroke
10.3760/cma.j.issn.1673-4165.2021.02.007
- VernacularTitle:长链非编码RNA H19：缺血性卒中的治疗靶点
- Author:
Liyuan ZHONG
;
Junfen FAN
;
Yumin LUO
- From:
International Journal of Cerebrovascular Diseases
2021;29(2):120-125
- CountryChina
- Language:Chinese
-
Abstract:
Ischemic stroke is a type of cerebrovascular disease with high morbidity, high mortality and high disability, which brings a huge medical burden to the society. Long non-coding RNA (lncRNA) H19 is closely associated with the pathophysiological mechanisms such as oxidative stress, inflammation, apoptosis, autophagy, and neurogenesis after ischemic stroke. It has received widespread attention in recent years. This article reviews the pathophysiological mechanism of lncRNA H19 in ischemic stroke, in order to provide new ideas for the diagnosis and treatment of ischemic stroke.
