Acute Pancreatitis Induced by Quetiapine in an Elderly Patient.
10.4235/jkgs.2015.19.3.176
- Author:
Hak Chul LEE
1
;
Jongkyoung CHOI
;
Jung A KOH
;
Seon Jae KIM
;
Seong Taek CHU
;
Si Eun KIM
;
Seung Kyu CHOI
;
Seung Woo NAM
;
Hyuk Chun KWON
;
Ju Won JUNG
;
In A JUNG
Author Information
1. Department of Internal Medicine, National Medical Center, Seoul, Korea. cjk@nmc.or.kr
- Publication Type:Case Report
- Keywords:
Acute pancreatitis;
Quetiapine;
Delirium
- MeSH:
Abdominal Pain;
Aged*;
Amylases;
Delirium;
Humans;
Korea;
Lipase;
Male;
Pancreatitis*;
Recurrence;
Risk Factors;
Quetiapine Fumarate
- From:Journal of the Korean Geriatrics Society
2015;19(3):176-180
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Quetiapine is an atypical antipsychotic that is frequently used to manage delirium in geriatric patients. Acute pancreatitis associated with quetiapine has rarely been reported. A 70-year-old male presented with severe abdominal pain a few hours after taking a dose of quetiapine prescribed for delirium. Despite the lack of risk factors of pancreatitis in his medical history, the patient had a slight increase of serum lipase and amylase levels. His general condition improved on discontinuation of quetiapine. A month later, quetiapine was readministered for the recurrence of delirium. Subsequently, the patient developed the same symptom with a significant increase in serum pancreatic enzyme levels, confirming that quetiapine induced the pancreatitis. We reported the first case of quetiapine-induced pancreatitis in Korea, together with a review of the literature.
