Relationship between vitamin D and the incidence and prevention of type 1 diabetes mellitus
10.3760/cma.j.issn.1673-4408.2021.05.007
- VernacularTitle:维生素D与1型糖尿病的发病及防治
- Author:
Xin GUAN
;
Xuewen YUAN
;
Qianqi LIU
- From:
International Journal of Pediatrics
2021;48(5):314-317
- CountryChina
- Language:Chinese
-
Abstract:
Type 1 diabetes mellitus(T1DM)is a chronic, immune-mediated disease characterised by the destruction of insulin-producing cells.The specific pathogenesis of T1DM has not been clarified.It is mainly believed that the occurrence of T1DM is caused by the joint action of genetic and environmental factors.The occurrence, development, treatment and prevention of T1DM are urgent problems to be solved.A number of studies have found that vitamin D is involved in the pathological process of many autoimmune diseases and is related to cell proliferation, differentiation, apoptosis and other mechanisms.Vitamin D may play a key role in the pathological mechanism of T1DM.Here we review the relationship between the incidence, prevention and treatment of T1DM and vitamin D.
