Kawasaki disease shock syndrome in children
10.3760/cma.j.issn.1673-4408.2021.05.002
- VernacularTitle:儿童川崎病休克综合征临床研究进展
- Author:
Ping HUANG
;
Xiaoyan LIU
- From:
International Journal of Pediatrics
2021;48(5):295-298
- CountryChina
- Language:Chinese
-
Abstract:
Kawasaki disease shock syndrome (KDSS)is a critical state of Kawasaki disease(KD)characterized by peripheral circulatory perfusion disorder and hypotension.The main causes of shock include cytokine imbalance, myocardial dysfunction and vasculitis with continuous capillary leakage.Compared with KD, KDSS shows longer fever duration, more severe inflammatory reaction, more obvious increase of D-dimer level, higher incidence of cardiovascular system abnormalities and multiple organ dysfunction, and higher proportion of unresponsive IVIG and glucocorticoid use.The early clinical manifestations and laboratory examination results of KDSS are not typical, so it is difficult to make an earlier diagnosis.The therapy of KDSS mainly includes anti-shock therapy and anti-inflammatory therapy may be associated with faster remission of shock and inflammation and better improvement of long-term prognosis.Many factors are related to the occurrence and development of KDSS.
