Progress of the protective mechanism of vitamin D on chronic kidney disease
10.3760/cma.j.issn.1673-4408.2021.04.014
- VernacularTitle:维生素D对慢性肾脏病保护机制研究进展
- Author:
Zhenzhen YUAN
;
Xiaoshan SHAO
- From:
International Journal of Pediatrics
2021;48(4):276-279
- CountryChina
- Language:Chinese
-
Abstract:
1,25(OH) 2 vitamin D 3 is the most effective status of vitamin D in the body.It will play a biological active role when it combines with the receptor of vitamin D. It is common in the chronic kidney disease patients who are lack of vitamin D. The research finds that among the chronic kidney disease patients, in addition to the classic role of vitamin D in regulating calcium and phosphorus metabolism, it can also protect the kidney and delay the progress of chronic kidney disease by blocking the renin-angiotensin system, inhibiting inflammation, reducing podocyte damage and delaying renal fibrosis, etc.This article summarizes the protection mechanism of Vitamin D in the chronic kidney diseases.
