Advances in molecular genetics of electrical status epilepticus during sleep in children
10.3760/cma.j.issn.1673-4408.2021.03.009
- VernacularTitle:儿童睡眠中癫痫性电持续状态的分子遗传学研究进展
- Author:
Fang ZHENG
;
Hua WANG
- From:
International Journal of Pediatrics
2021;48(3):182-185
- CountryChina
- Language:Chinese
-
Abstract:
Electrical status epilepticus during sleep(ESES)is a special electroencephalography in children.It is involved in a variety of epileptic syndromes and can lead to different degrees of degradation of movement, cognition, behavior, language.At present, the cause of ESES is still unknown.According to literature reports, 8 pathogenic genes have been found to be related to ESES, namely GRIN2A, CNKSR2, SCN2A, KCNA2, KCNQ2, KCNB1, SLC6A1 and WAC genes.In this review, progress of ESES molecular genetics are discussed.
