Phenotypes and endotypes of difficult-to-treat asthma
10.3760/cma.j.issn.1673-4408.2021.03.006
- VernacularTitle:难治性哮喘的分型研究进展
- Author:
Yuntian DENG
;
Yuanyuan QI
- From:
International Journal of Pediatrics
2021;48(3):168-172
- CountryChina
- Language:Chinese
-
Abstract:
Difficult-to-treat asthma is a complex disease with poor response to high-dose inhaled corticosteroids plus a second controller or need high levels of treatment to maintain control.Difficult-to-treat asthma represents a significant clinical challenge and a heavy medical burden due to its heterogeneity.Identification of the phenotypes and endotypes in difficult-to-treat asthma is very helpful for individualized therapy.This review summarizes the latest studies on the classification of difficult-to-treat asthma in order to provide evidence for the diagnosis and treatment of difficult-to-treat asthma in children.
