Clinical application, drug resistance and adverse effects of azithromycin
10.3760/cma.j.issn.1673-4408.2021.02.008
- VernacularTitle:阿奇霉素的临床应用、耐药及不良反应
- Author:
Xifeng TANG
;
Yongdong YAN
- From:
International Journal of Pediatrics
2021;48(2):104-107
- CountryChina
- Language:Chinese
-
Abstract:
As the second generation macrolide antibiotic, except for antibacterial effects, azithromycin can down-regulate inflammatory responses, reduce mucus secretion and inhibit bacterial biofilms.In addition to the infectious diseases caused by atypical pathogens, viral or bacterial, chronic diseases including cystic fibrosis, chronic rhinosinusitis, asthma, gastroparesis and otherdiseases can be treated with azithromycin.Clinicians should pay more attention to drug resistance and adverse reactions in infant.The article will review the progress of clinical application of azithromycin in recent years and the strategies for drug resistance and adverse effects.
