Intrapericardial fibrinolysis for purulent pericarditis in children
10.3760/cma.j.issn.1673-4408.2021.02.005
- VernacularTitle:心包内溶纤维蛋白治疗在儿童化脓性心包炎中的应用进展
- Author:
Buchun JIANG
;
Chenmei ZHANG
- From:
International Journal of Pediatrics
2021;48(2):91-94
- CountryChina
- Language:Chinese
-
Abstract:
Purulent pericarditis is still a life-threatening disease for children.Utilizing antibiotics and performing completely drainage of pus are the major treatment options.Constrictive pericarditis is an important complication of purulent pericarditis.Intrapericardial fibrinolysis can effectively reduce fibrin deposition in pericardium, prevent pericardium adhesion and fibrosis, therefore it will prevent constrictive pericarditis.However, it is seldom used in the treatment of children with purulent pericarditis.This article reviews the domestic and international reports on intrapericardial fibrinolysis in children with purulent pericarditis, introduces the indications, mechanisms, treatment protocols, effectiveness studies and complications of intrapericardial fibrinolysis, thus providing a reference for the treatment protocol of children with purulent pericarditis.