Progress of Sirtuins family in bronchial asthma
10.3760/cma.j.issn.1673-4408.2021.01.004
- VernacularTitle:Sirtuins家族在支气管哮喘中的研究进展
- Author:
Xingqian LAI
;
Lin TONG
;
Zhimin CHEN
- From:
International Journal of Pediatrics
2021;48(1):14-18
- CountryChina
- Language:Chinese
-
Abstract:
Silent information adjustment factor(Sirtuins)are Ⅲ class histone deacetylase on the nicotinamide adenine dinucleotide(NAD +), and regulate various enzyme activities and biological processes.Recent studies have found that members of the Sirtuins family are closely related to the occurrence of bronchial asthma.This review summarizes the role of the Sirtuins family in the pathogenesis of bronchial asthma and provides a basis for the Sirtuins family as a potential therapeutic target for bronchial asthma.