Adult chronic active Epstein-Barr virus infection-related T-cell lymphoma complicated with hemophagocytic syndrome: report of one case and review of literature

VernacularTitle:成年人慢性活动性EB病毒感染相关T细胞淋巴瘤合并噬血细胞综合征一例并文献复习
Author: Dan LIU ; Xiao MA ; Shanshan JIANG ; Dongyang LI ; Yutong JING ; Mengjia HOU ; Xiaohui HU
From: Journal of Leukemia & Lymphoma 2021;30(4):220-223
CountryChina
Language:Chinese
Abstract: Objective:To investigate the pathological change mechanism of patients with chronic active Epstein-Barr virus infection (CAEBV).Methods:The clinical manifestations, laboratory examinations, diagnosis and treatment of one CAEBV patient in Suzhou Hongci Hematology Hospital of Jiangsu Province were retrospectively analyzed with review of related literature.Results:Combined with the results of laboratory, lymph node biopsy and bone marrow tests in different periods, the patient initially showed lymphoproliferative disease, and gradually transformed into lymphoma with the diagnosis results of EB virus-related lymphocyte clones in different periods. The patient received the corresponding treatment plan in different periods, but eventually died due to hemophagocytic syndrome and rapid progress of the disease.Conclusion:CAEBV may cause lymphocytes to gradually evolve from polyclonal to monoclonal state.