Comparing the efficacy of periprostatic nerve block alone versus periprostatic nerve block plus oral tramadol plus paracetamol tablet for pain control of patients during and after transrectal biopsy of the prostate gland: A randomized controlled trial.
- Author:
Eric Roudel C. Ecalnir
1
;
Kathleen R. Gonzales
1
;
Eduardo M. Anonuevo
1
;
Author Information
- Publication Type:Journal Article
- Keywords: periprostatic nerve block; transrectal ultrasound; prostate biopsy
- MeSH: Male; Prostate; Nerve Block; Biopsy; Ultrasonography
- From: Philippine Journal of Urology 2020;30(1):43-48
- CountryPhilippines
- Language:English
-
Abstract:
OBJECTIVE:To compare the efficacy of periprostatic nerve block (PPNB) alone versus periprostatic nerve block plus oral Tramadol+Paracetamol Tablet for pain control during and after transrectal ultrasound-guided (TRUS) biopsy of the prostate gland.
METHODS:This was a double-blind, placebo-controlled randomized clinical trial. The authors randomized 40 male patients each to either PPNB or PPNB plus oral tramadol and paracetamol (37.5mg/325mg) an hour prior to prostate biopsy. A ten-point visual analog scale was used to measure pain intensity and was recorded upon insertion of the ultrasound probe, during the biopsy, and one hour after the procedure.
RESULTS:The two groups were similar in terms of baseline characteristics. Reductions in pain scores were statistically significantly different (p<.001) for each group when comparing pain from at point of insertion of the probe versus during biopsy and versus one-hour post-operatively. However, when comparing the two groups, the pain scores were not statistically significantly different upon insertion of the probe (p=.68), during the biopsy (p=.26) and one-hour post-operatively (p=.54).
CONCLUSION:Tramadol and paracetamol combination in addition to periprostatic nerve block produces pain relief similar to standard periprostatic nerve block alone. - Full text:106-Full Research Text-291-1-10-20200924 (2).pdf
