Review of anti-atherosclerosis mechanism of a TCM formula

VernacularTitle:中药复方抗动脉粥样硬化作用机制的研究进展
Author: Bin XIE ¹ ; Xing YUAN ¹ ; Xike XU ¹ ; Runhui LIU ¹
Author Information

1. Department of Natural Medicinal Chemistry, School of Pharmacy, Naval Medical University, Shanghai 200433, China.
Keywords: TCM formula; atherosclerosis; mechanism; review
From: Journal of Pharmaceutical Practice 2021;39(4):295-298
CountryChina
Language:Chinese
Abstract: The global morbidity and mortality of cardiovascular diseases remain high. Atherosclerosis is an important pathological basis of cardiovascular diseases, and its pathogenic mechanism has not been fully clarified. It was reported that pathogenic mechanism of atherosclerosis is related to vascular endothelial cell injury, lipid metabolism disorder, inflammatory reaction, imbalance between autophagy and apoptosis, et al. Traditional Chinese medicine(TCM) formula has shown good effects in the prevention and treatment of atherosclerosis. There are a lot of studies that showed the anti-atherosclerosis effect and the mechanism of TCM formula. In this paper, we reviewed the mechanism of anti-atherosclerosis action of TCM formula by summarizing the research literatures in the past five years, and provide reference for the further systematic study of anti-atherosclerosis effect of TCM formula.