Expermental chemotherapeutic effects of niclofolan (Bayer 9015, Bilevon) on the animals infected with Paragonimus westermani or P. iloktsuenensis.
10.3347/kjp.1976.14.2.140
- Author:
Han Jong RIM
1
;
Myung Se KIM
;
Joung Hwan HA
;
Dong Shik CHANG
Author Information
1. Department of Parasitology and Institute for Tropical Endemic Diseases, College of Medicine, Korea University, Seoul, Korea.
- Publication Type:Original Article
- MeSH:
parasitology-helminth-trematoda;
Paragonimus iloktsuenensis;
paragonimiasis;
Paragonimus westermani;
dog;
cat;
rat;
niclofolan-chemotherapy;
niclofolan
- From:The Korean Journal of Parasitology
1976;14(2):140-146
- CountryRepublic of Korea
- Language:English
-
Abstract:
The new drug niclofolan (bayer 9015, Bilevon), 5,5'-dichloro-2,2'-dihydroxy-3, 3'-dinitrobiphenyl, has been used in the treatment of Paragonimus westermani in dogs and cats and P. iloktsuenensis in rats. It was proved that administration of daily dose of 1.0 mg/kg body weight for 3 days or in 2 doses of 2.0 mg/kg body weight by alternate days were evidently effective for the infected dogs, cats and rats with the lung flukes, and toxic manifestations were not found.
