Widespread lichen planus pigmentosus in a 32-year-old Filipino male treated with low dose isotretinoin and topical tacrolimus

Author: Nel Muriel B. Lee ¹ ; Heirich Fevrier P. Manalili ¹ ; Johannes F. Dayrit ²
Author Information

1. Resident Physician, Department of Dermatology, Research Institute for Tropical Medicine, Research Drive, Alabang, Muntinlupa
2. Consultant, Department of Dermatology, Research Institute for Tropical Medicine, Research Drive, Alabang, Muntinlupa
Publication Type:Journal Article
Keywords: LPP, pigmentary
MeSH: Isotretinoin; Dermoscopy; Pigmentation
From: Journal of the Philippine Dermatological Society 2020;29(1):122-124
CountryPhilippines
Language:English
Abstract: INTRODUCTION: Lichen Planus Pigmentosus (LPP) is a pigmentary disorder of unknown etiology, presenting with CASE REPORT: We report a case of a 32-year-old healthy male with widespread lichen planus pigmentosus, treated with clobetasol dipropionate 0.05% ointment, tacrolimus 0.1% ointment, and lowdose isotretinoin (0.1 to 0.2 mkd) showing a decrease in the progression and hyperpigmentation of patches and plaques after six months. CONCLUSION: Based on our case and recent studies, low-dose oral isotretinoin, in combination with topical tacrolimus and topical corticosteroids, may show promising outcomes in treating cases of widespread lichen planus pigmentosus.
Full text:15_What-lies-beneath_LPP_Lee.pdf