Simultaneous determination of three chlorobenzene compounds in workplace air by portable gas chromatography-mass spectrometry
10.11763/j.issn.2095-2619.2020.03.019
- Author:
Jiaheng HE
1
,
2
;
Yuanyuan SHE
;
Guanlin CHEN
;
Weifeng RONG
1
,
2
;
Ruibo MENG
1
,
2
;
Jiawen HU
1
,
2
;
Banghua WU
1
,
2
Author Information
1. Guangdong Province Hospital for Occupational Disease Prevention and Treatment
2. Guangdong Provincial Key Laboratory of Occupational Disease Prevention and Treatment Guangzhou, Guangdong 510300, China
- Publication Type:Journal Article
- Keywords:
Portable;
Gas chromatography-mass spectrometry;
Chlorobenzene;
p-Dichlorobenzene;
o-Dichlorobenzene;
Workplace;
Air
- From:
China Occupational Medicine
2020;47(03):339-342
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To establish a method for simultaneous determination of chlorobenzene, p-dichlorobenzene and o-dichlorobenzene in workplace air by portable gas chromatography-mass spectrometry(GC-MS). METHODS: The portable GC-MS heat tracing sampling probe was used for sampling. Samples were separated with LTM DB-5 MS rapid chromatographic column. The qualitative analysis was based on retention times and characteristic ions, and the quantification was based on standard curves. RESULTS: The linear correlation coefficient of this method was higher than 0.999 6. The minimum detectable concentrations were 0.03, 0.03 and 0.06 mg/m~3, and the minimum quantification concentrations were 0.10, 0.10 and 0.20 mg/m~3. The recovery rates were 84.68%-92.61%, 86.27%-93.92% and 82.31%-92.36% respectively for three chlorobenzenes compounds. The within-run relative standard deviations(RSD) were 8.51%-9.34%, 7.93%-9.19%, 5.47%-7.48% respectively for three chlorobenzenes compounds, the between-run RSD were 7.29%-9.73%, 8.08%-10.04% and 5.19%-5.98% respectively for three chlorobenzenes compounds. CONCLUSION: The portable GC-MS could be used for qualitative and quantitative detection of three chlorobenzenes compounds in workplace air.
