Determination of N-methyl-2-pyrrolidone in workplace air by solvent desorption-gas chromatography
10.11763/j.issn.2095-2619.2019.02.019
- Author:
Ruibo MENG
1
;
Weifeng RONG
1
;
Jiawen HU
1
;
Jiaheng HE
1
;
Zidan YAN
;
Yuanyuan SHE
;
Banghua WU
1
Author Information
1. Guangdong Province Hospital for Occupational Disease Prevention and Treatment,Guangdong Province Key Laboratory of Occupational Disease Prevention and Treatment Guangzhou, Guangdong 510300, Chinangdong
- Publication Type:Journal Article
- Keywords:
Workplace;
Air;
N-Methyl-2-pyrrolidone;
Solvent desorption;
Gas chromatography
- From:
China Occupational Medicine
2019;46(02):229-232
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To establish a method for determination of N-methyl-2-pyrrolidone(NMP) in workplace air by solvent desorption-gas chromatography. METHODS: NMP in the workplace air was collected with activated carbon tube and desorbed with methanol ∶dichloromethane(5 ∶95, V/V). After desorption, it was separated by capillary column separation, and detected by flame ionization detector. RESULTS: The good linear concentration of NMP was 0.51-4 108.00 mg/L. The correlation coefficient was 0.999 9. The detection limit was 0.08 mg/L(calculated by 3 times of standard deviation). The average desorption efficiency was 101.68%-103.44%. The within-run and between-run relative standard deviations were 1.94%-3.97% and 0.97%-2.26%, respectively. The sample could be stored at room temperature for at least 14 days. CONCLUSION: The developed method is suitable for the determination of NMP in workplace air.
